LSJM: Estimate Location-Scale Joint Models

Estimation of mixed models including a subject-specific variance that can be time- and covariate-dependent or defined for within- and between-visit variability. In the joint modeling framework, the package handles left truncation, interval censoring, and multistate models, and allows a flexible dependence structure between competing events and the longitudinal marker. Estimation is performed in a frequentist framework using the Marquardt-Levenberg algorithm. Methods are described in Courcoul et al. (2025) <doi:10.1002/sim.70244> and in Courcoul et al. (2026) <doi:10.1002/bimj.70123>.

Version: 0.1.0
Depends: R (≥ 3.5.0)
Imports: Rcpp, marqLevAlg, survival, flexsurv, ggplot2, splines, spacefillr, survminer, foreach, doParallel, SmoothHazard, parallel, mvtnorm, dplyr
LinkingTo: Rcpp, RcppArmadillo
Published: 2026-08-04
DOI: 10.32614/CRAN.package.LSJM (may not be active yet)
Author: Léonie Courcoul [aut, cre], Antoine Barbieri [aut], Hélène Jacqmin-Gadda [aut]
Maintainer: Léonie Courcoul <courcoul.leonie498 at gmail.com>
License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
NeedsCompilation: yes
Materials: README, NEWS
CRAN checks: LSJM results

Documentation:

Reference manual: LSJM.html , LSJM.pdf

Downloads:

Package source: LSJM_0.1.0.tar.gz
Windows binaries: r-devel: not available, r-release: not available, r-oldrel: not available
macOS binaries: r-release (arm64): not available, r-oldrel (arm64): not available, r-release (x86_64): not available, r-oldrel (x86_64): not available

Linking:

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